Author : Alptekin Tosun -İsmail Şerifoğlu -Bilge Çakır
Aim: The aim of the study is to demonstrate the relationship between the number and distribution of microbleeding focuses with degrees of periventricular ischemia on magnetic resonance imaging (MRI) by using T2W GRE in lacunar infarct. Method: 79 patients with stroke were examined on MRI by using T2W GRE. Periventricular hyperintensity (PVH) grouped on 4 degrees by using scoring system. Microbleedings defined as a well bordered small hemosiderin deposits appear hypointense on T2W gradient echo sequence. Results: One or more microbleeding focuses had found on T2W GRE in 49.6%. Microbleedings were existed lacunar infarct in 93.7%. Pearson chi-square analysis revealed a significant relation with periventricular ischemia severity and the number of microbleedings (p<0,01). Spearman’s correlation analysis showed an advanced positive relationship between number of lacunar infarcts and number of microbleedings (r=0,429; p<0,01), number of lacunar infarcts and severity of periventricular hyperintensity (r=0,400; p<0,01) and severity of periventricular hyperintensity and number of microbleedings (r=0,773; p<0,01). Conclusion: This study revealed the relationship between lacunar infarct, periventricular white matter ischemia and hypointens focuses on T2W GRE. This MRI sequence has a role on diagnosis and treatment planning especially cerebrovascular diseases in middle and advanced ages.
Keywords: Microangiopathy, T2 weighted graident echo, cerebrovasculary, dementia